DCIS Dilemmas: Discussions about Ductal Carcinoma In Situ & the Research Behind It, by Deborah E. Collyar, Philippe D. Gascard, Thea D. Tisty
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DCIS Dilemmas: Discussions about Ductal Carcinoma In Situ & the Research Behind It, by Deborah E. Collyar, Philippe D. Gascard, Thea D. Tisty
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Women often think that their risk of getting Ductal Carcinoma In Situ (DCIS) or Invasive Breast Cancer (IBC) is much higher than real numbers show. This fear is often fed by new stories about research, and sometimes by their own doctors. Many doctors and researchers say that DCIS is not Invasive Breast Cancer (IBC) because it stays in the breast duct. HOWEVER... DCIS is also called Stage 0 breast cancer, and is treated as if it were IBC. There are many dilemmas about DCIS, and this book tries to clear them up. We know how easy it is to end up more confused after looking at different websites, books, and research results. We present a new way to approach DCIS that combines the latest research with practical information. Even though we state things plainly, many scientific resources and references were used to make sure this book is accurate. Please be aware that those resources may use older language that we are learning is not accurate for DCIS. For example, DCIS lesions do not have the ability to "recur," even though this term is commonly used by many scientists and doctors. You will learn about DCIS and how it fits into breast diseases, including breast cancer. The process of getting diagnosed is also explained, as are the different types of treatments that are commonly given for DCIS. Risks are also explained clearly. This includes the risk of being diagnosed with DCIS, as well as the risk of getting another DCIS or a future Invasive Breast Cancer. This book also highlights the various kinds of ongoing research for DCIS. A list of terms, and additional resources and references are also included to help you find more detailed information. We hope this book offers useful information to help you make decisions about DCIS, and look forward to hearing how you use it! Deborah Collyar (1st author): Deborah Collyar was breaking glass ceilings in a computer company when she found a lump at age 32. A mastectomy, chemotherapy, radiation, and chemo-induced menopause produced a new outlook on career and life, especially after delivering a healthy baby in 1993. Ductal Carcinoma in Situ (DCIS), another breast cancer, and husband Bob's lung cancer sent them blazing new trails by injecting patients directly into the research process, from policies, idea generation and grant proposals, to development, clinical trials, and delivering 'better results to people faster. Philippe Gascard (2nd author): Over the last 30 years, Dr. Philippe Gascard has built a solid background in protein and lipid chemistry, molecular biology, cell biology, systems biology and epigenetics. Over the past 10 years, Dr. Gascard has gained extensive expertise in breast cancer biology with an emphasis on epigenetics, biomarker discovery and multiplex immunohistochemistry. An active participant of the Integrative Cancer Biology Program (ICBP), he was the Director of the Central Pathology Laboratory for the UCSF Roadmap Epigenetics Mapping Consortium (REMC) from 2008 to 2014. As researcher and project manager in Dr. Tlsty's laboratory since 2008, he has been closely involved in the writing and scientific conceptualization of multiple grant applications, including a recently funded award aimed at identifying new biomarkers for prediction of outcome in patients diagnosed with DCIS. Thea Tlsty (3rd author): Dr. Thea Tlsty has over 25 years of experience studying human cells and the earliest steps of malignancy. The model systems she developed contribute to clinical utility by identifying molecular stromal-epithelial interactions that facilitate tumor progression in the breast and prostate. These analyses have led her to identify consequences of epithelial stress that lead to the activation of pro-tumorigenic tissue phenotypes that helps activate a multicellular stromal program shared by high mammographic density and tumor tissues.
DCIS Dilemmas: Discussions about Ductal Carcinoma In Situ & the Research Behind It, by Deborah E. Collyar, Philippe D. Gascard, Thea D. Tisty- Amazon Sales Rank: #961408 in eBooks
- Published on: 2015-10-13
- Released on: 2015-10-13
- Format: Kindle eBook
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Most helpful customer reviews
1 of 1 people found the following review helpful. A must read for women diagnosed with DCIS! By Amazon Customer It's great to see a current book regarding the DCIS Dilemma. I have been passionately researching this topic for 6 years due to a DCIS diagnosis which I feel I was mis-treated and over-treated for. After a two year journey and 3 surgeries, I said NO MORE! I created two websites (DCIS 411 and DCIS Redefined) to help women diagnosed with DCIS take more time to understand what DCIS is and to find support and resources for integrative solutions and "active surveillance." There is so little information and support out there for women seeking a less aggressive approach to DCIS so I greatly appreciate the very intensive research that the authors have put into this comprehensive book discussing a difficult and controversial topic. It is such a complicated and confusing diagnosis and far too many women are rushed into very drastic life-altering treatments -- often times in a panic. There is now solid research showing a great deal of the "standard of care" treatments are unnecessary -- and there is great harm being done to women. This book brings many of these controversies to light. The issue of DCIS over-treatment made international news in 2015 with a large study that came out stating that there was no survival benefit to any of the current standard of care treatments., Many doctors are not fully informing their patients of the potential risks and harms of mammograms -- one of which is a diagnosis of DCIS -- which opens to the can of worms and dilemmas this book discusses. Too many women are being needlessly harmed with very drastic treatments (as if they have invasive cancer). This needs to be investigated further so that women can make healthier, more common-sense decisions that are truly in their best interest based on their individual pathology and true risk assessment and not just based in fear and one-size-fits-all radical treatments. It's time women become informed and empowered regarding mammograms, DCIS and breast cancer prevention and risk reduction. This book is an excellent resource for any woman who is getting screening mammograms due to the high rate of false positives and suspicious calcifications that may lead to biopsies and the terrible dilemmas associated with a DCIS diagnosis.
1 of 1 people found the following review helpful. Become an Empowered Patient By Amazon Customer DCIS or stage zero breast cancer presents many challenges. Fewer diagnoses provide such a wide range of available treatments. This book very carefully and clearly lays out the questions that those individuals with the DCIS diagnosis confront. The DCIS Dilemmas provides the information to help those have been diagnosed with DCIS make an informed decision about how they want to proceed.As someone who co-facilitates a support group for DCIS, I continually see women struggle and agonize over what they should do. The two biggest issues that bring women to the group are fear of recurrence and how much treatment is necessary. For them the likelihood of recurrence gets buried in statistical manipulation and the suggested DCIS treatment plan often resembles that of someone with far more advanced breast cancer. So often I hear women say their doctors tell them what they should do without letting them know about their options. I personally know that with knowledge and information about breast cancer comes empowerment. It helped me alleviate fear and make educated, not emotional decisions. This is a must read. I have recommended this book to those who attended the group in the past as well as the current members. Each of us that have had this diagnosis needs to know more.
1 of 1 people found the following review helpful. This book gives good and accurate information about DCIS (ductal carcinoma in situ) ... By Amazon Customer This book gives good and accurate information about DCIS (ductal carcinoma in situ) and is likely to be highly recommended to those wanting more information about DCIS. Whether you are a patient diagnosed with DCIS, or know someone diagnosed with DCIS, or are confused about DCIS and want to learn more, this book will have something for you.The book is written in a way that is easy to understand. The information is based on evidence and the book clearly identifies key references and studies. The links throughout the document take you to places to learn more about specific topics. The book uses illustrations for those who are visual learners. The way the book is formatted allows for easy reading with many bulleted lists and key messages are highlighted in red. The list of terms is a reference that anyone diagnosed with breast cancer will find useful. The resources and references are expansive and useful.I will definitely recommend this book for those diagnosed with DCIS to learn more about treatment options. Today with many patients facing important decisions about treatment choices, there is a need for accurate information. This book provides this information and will help patients make these important decisions.
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